Human NCI-H3122 Tumor Cell Line

The Human NCI-H3122 Tumor Cell Line is a vital resource in cancer research, particularly for studying lung cancer biology. Originating from a human lung adenocarcinoma, this cell line is characterized by specific genetic alterations, including an EML4-ALK fusion, which makes it an ideal model for investigating targeted therapies and drug resistance mechanisms. Researchers utilize the Human NCI-H3122 Tumor Cell Line to evaluate the efficacy of ALK inhibitors and to explore novel therapeutic strategies aimed at overcoming resistance. The insights gained from studies using this cell line contribute significantly to advancing personalized medicine approaches and developing more effective treatments for patients with lung cancer.